Visit one of Europe's oldest museums, Uffizi Gallery. Explore the development of art through the Middle Ages and Italian Renaissance. The Uffizi Gallery is home to the priceless Medici family collection of ancient statues and busts that line the hallways and are ancient Roman copies of extinct Greek sculptures. Explore the portrait of Anna Maria Luisa de' Medici, the last surviving member of the Medici responsible for donating all of the family's collections to the city. Admire masterpieces by Giotto, Cimabue, and Duccio di Buoninsegna and the paintings of Venus de Milo by Botticelli, the Annunciation by Leonardo da Vinci and the only panel painting in the world by Michelangelo. Visit the museum's highlights from each era as you follow a sequential itinerary that will take you back in time. Start with Tuscany's Byzantine art before gradually moving on to the magnificent Renaissance. Take advantage of this chance to look around the gallery on your own.